![Activation of Wnt/β‐catenin signaling restores insulin sensitivity in insulin resistant neurons through transcriptional regulation of IRS‐1 - Tian - 2021 - Journal of Neurochemistry - Wiley Online Library Activation of Wnt/β‐catenin signaling restores insulin sensitivity in insulin resistant neurons through transcriptional regulation of IRS‐1 - Tian - 2021 - Journal of Neurochemistry - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/7dcf649f-9876-4ede-bd99-23c2e15f5192/jnc15277-fig-0009-m.png)
Activation of Wnt/β‐catenin signaling restores insulin sensitivity in insulin resistant neurons through transcriptional regulation of IRS‐1 - Tian - 2021 - Journal of Neurochemistry - Wiley Online Library
![Serine/Threonine phosphorylation of IRS-1. IRS-1 interacts with the... | Download Scientific Diagram Serine/Threonine phosphorylation of IRS-1. IRS-1 interacts with the... | Download Scientific Diagram](https://www.researchgate.net/publication/304626696/figure/fig2/AS:378714522177537@1467303986421/Serine-Threonine-phosphorylation-of-IRS-1-IRS-1-interacts-with-the-juxtamembrane-domain.png)
Serine/Threonine phosphorylation of IRS-1. IRS-1 interacts with the... | Download Scientific Diagram
![IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling | eLife IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling | eLife](https://iiif.elifesciences.org/lax/32893%2Felife-32893-fig4-v1.tif/full/,1500/0/default.jpg)
IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling | eLife
![Expression and function of the insulin receptor substrate proteins in cancer | Cell Communication and Signaling | Full Text Expression and function of the insulin receptor substrate proteins in cancer | Cell Communication and Signaling | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2F1478-811X-7-14/MediaObjects/12964_2009_Article_62_Fig3_HTML.jpg)
Expression and function of the insulin receptor substrate proteins in cancer | Cell Communication and Signaling | Full Text
![GHR signaling via insulin receptor substrate-1 (IRS-1) and IRS-2. Solid... | Download Scientific Diagram GHR signaling via insulin receptor substrate-1 (IRS-1) and IRS-2. Solid... | Download Scientific Diagram](https://www.researchgate.net/publication/12406355/figure/fig5/AS:601579195490304@1520439065146/GHR-signaling-via-insulin-receptor-substrate-1-IRS-1-and-IRS-2-Solid-molecules-and.png)
GHR signaling via insulin receptor substrate-1 (IRS-1) and IRS-2. Solid... | Download Scientific Diagram
![Hepatitis C Virus Activates the mTOR/S6K1 Signaling Pathway in Inhibiting IRS-1 Function for Insulin Resistance | Journal of Virology Hepatitis C Virus Activates the mTOR/S6K1 Signaling Pathway in Inhibiting IRS-1 Function for Insulin Resistance | Journal of Virology](https://journals.asm.org/cms/10.1128/jvi.00050-12/asset/cef1da50-072e-466c-bcfb-b59fdc3849a0/assets/graphic/zjv9990960690001.jpeg)
Hepatitis C Virus Activates the mTOR/S6K1 Signaling Pathway in Inhibiting IRS-1 Function for Insulin Resistance | Journal of Virology
![Serine phosphorylation of insulin receptor substrate-1: a novel target for the reversal of insulin resistance. | Semantic Scholar Serine phosphorylation of insulin receptor substrate-1: a novel target for the reversal of insulin resistance. | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/87b2f2ddfea4c00a47c05f1e583047fc45d30b22/2-Figure1-1.png)
Serine phosphorylation of insulin receptor substrate-1: a novel target for the reversal of insulin resistance. | Semantic Scholar
![JCI - Insulin/IGF-1 and TNF-α stimulate phosphorylation of IRS-1 at inhibitory Ser307 via distinct pathways JCI - Insulin/IGF-1 and TNF-α stimulate phosphorylation of IRS-1 at inhibitory Ser307 via distinct pathways](https://dm5migu4zj3pb.cloudfront.net/manuscripts/10000/10934/medium/JCI0110934.f9.jpg)
JCI - Insulin/IGF-1 and TNF-α stimulate phosphorylation of IRS-1 at inhibitory Ser307 via distinct pathways
IRS-1/PI3K/Akt pathway and miRNAs are involved in whole grain highland barley (Hordeum vulgare L.) ameliorating hyperglycemia of db/db mice - Food & Function (RSC Publishing)
![Insulin receptor substrate-1 (IRS-1) mediates progesterone receptor-driven stemness and endocrine resistance in oestrogen receptor+ breast cancer | British Journal of Cancer Insulin receptor substrate-1 (IRS-1) mediates progesterone receptor-driven stemness and endocrine resistance in oestrogen receptor+ breast cancer | British Journal of Cancer](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41416-020-01094-y/MediaObjects/41416_2020_1094_Figa_HTML.png)
Insulin receptor substrate-1 (IRS-1) mediates progesterone receptor-driven stemness and endocrine resistance in oestrogen receptor+ breast cancer | British Journal of Cancer
![Model of IRS-1-mediated signaling events. During insulin stimulation,... | Download Scientific Diagram Model of IRS-1-mediated signaling events. During insulin stimulation,... | Download Scientific Diagram](https://www.researchgate.net/publication/14447471/figure/fig3/AS:282708572950528@1444414384026/Model-of-IRS-1-mediated-signaling-events-During-insulin-stimulation-IRS-1-is.png)
Model of IRS-1-mediated signaling events. During insulin stimulation,... | Download Scientific Diagram
![Regulation of insulin receptor substrate-1 by mTORC2 (mammalian target of rapamycin complex 2). | Semantic Scholar Regulation of insulin receptor substrate-1 by mTORC2 (mammalian target of rapamycin complex 2). | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/4853a7d32a884037db14cc3df14dc4c84e99cfcd/2-Figure1-1.png)
Regulation of insulin receptor substrate-1 by mTORC2 (mammalian target of rapamycin complex 2). | Semantic Scholar
![Frontiers | The Novel Functions of High-Molecular-Mass Complexes Containing Insulin Receptor Substrates in Mediation and Modulation of Insulin-Like Activities: Emerging Concept of Diverse Functions by IRS-Associated Proteins Frontiers | The Novel Functions of High-Molecular-Mass Complexes Containing Insulin Receptor Substrates in Mediation and Modulation of Insulin-Like Activities: Emerging Concept of Diverse Functions by IRS-Associated Proteins](https://www.frontiersin.org/files/Articles/141004/fendo-06-00073-HTML/image_m/fendo-06-00073-g001.jpg)
Frontiers | The Novel Functions of High-Molecular-Mass Complexes Containing Insulin Receptor Substrates in Mediation and Modulation of Insulin-Like Activities: Emerging Concept of Diverse Functions by IRS-Associated Proteins
![Insulin receptor substrate (IRS) 1 is reduced and IRS-2 is the main docking protein for phosphatidylinositol 3-kinase in adipocytes from subjects with non-insulin-dependent diabetes mellitus | PNAS Insulin receptor substrate (IRS) 1 is reduced and IRS-2 is the main docking protein for phosphatidylinositol 3-kinase in adipocytes from subjects with non-insulin-dependent diabetes mellitus | PNAS](https://www.pnas.org/cms/10.1073/pnas.94.8.4171/asset/d07fe909-7efb-483c-8206-54d84d7bf723/assets/graphic/pq0870377002.jpeg)
Insulin receptor substrate (IRS) 1 is reduced and IRS-2 is the main docking protein for phosphatidylinositol 3-kinase in adipocytes from subjects with non-insulin-dependent diabetes mellitus | PNAS
![Regulating insulin signaling and β-cell function through IRS proteins This paper is one of a selection of papers published in this Special Issue, entitled Second Messengers and Phosphoproteins—12th International Conference. Regulating insulin signaling and β-cell function through IRS proteins This paper is one of a selection of papers published in this Special Issue, entitled Second Messengers and Phosphoproteins—12th International Conference.](https://cdnsciencepub.com/cms/10.1139/y06-008/asset/images/large/y06-008f4.jpeg)
Regulating insulin signaling and β-cell function through IRS proteins This paper is one of a selection of papers published in this Special Issue, entitled Second Messengers and Phosphoproteins—12th International Conference.
![IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling | eLife IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling | eLife](https://iiif.elifesciences.org/lax/32893%2Felife-32893-fig1-v1.tif/full/1500,/0/default.jpg)